Make an appointment with your doctor if you notice that your lymph nodes feel hard or immovable. However, enlarged lymph nodes can also be a sign that other types of cancer, such as breast cancer, have spread (metastasized) to your lymph nodes. When they are, it’s usually related to lymphoma or leukemia, which both involve the lymphatic system. Swollen lymph nodes are rarely caused by cancer. HIV, mononucleosis, and immune system disorders can lead to swollen lymph nodes throughout your body. A tooth infection might cause swollen lymph nodes around your jaw. For instance, swollen lymph nodes in your neck may be due to an upper respiratory infection. The location of the reactive lymph nodes can help you narrow down the cause.
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